Author

J. Ying

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Bax· 1 shared A. Garancher· 1 shared A. J. Baldwin· 1 shared B. Lee· 1 shared B. Liu· 1 shared C. Bettegowda· 1 shared C. G. Eberhart· 1 shared C. Zhong· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. Bax

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Geometric Quantification of Cell Phenotype Transition Manifolds with Information Geometry

M. Huang, Y. Wang, J. Ying, H. Zhou, L. Zhang, W. Wang

The paper introduces SCIM, a method using information geometry to quantify cell phenotype transition manifolds by analyzing curvature and velocity in single-cell gene expression data.

bioRxiv · Dec 28, 2023Biophysics

Downregulation of NCL attenuates tumor formation and growth in cervical cancer by targeting the PI3K/AKT pathway

J. Ying, R. w. Pan, Z. h. Tang, J. y. Zhu, P. Ren, Y. Lou, E. y. Zhang, D. d. Huang, P. h. Hu, D. Li, Q. y. Bao, P. z. Li

This study shows that reducing NCL in cervical cancer cells inhibits tumor growth by suppressing the PI3K/AKT pathway and promoting apoptosis.

bioRxiv · Apr 1, 2021Cancer Biology

The long non-coding RNA lnc-HLX-2-7 is oncogenic in group 3 medulloblastomas

K. Katsushima, B. Lee, H. Kunhiraman, C. Zhong, R. Murath, J. Ying, B. Liu, A. Garancher, H. L. Monforte, I. Gonzalez-Gomez, S. Stapleton, R. Vibhakar, C. Bettegowda, R. J. Wechsler-Reya, G. Jallo, , R. J. Perera

This study identifies lnc-HLX-2-7 as an oncogenic lncRNA in group 3 medulloblastomas, showing it promotes tumor growth and is regulated by MYC and JQ1.

bioRxiv · Jun 8, 2020Cancer Biology

Local unfolding of the HSP27 monomer regulates chaperone activity

T. R. Alderson, J. Roche, H. Y. Gastall, I. Pritisanac, J. Ying, A. Bax, J. L. P. Benesch, A. J. Baldwin

This study shows that redox-induced monomerization of HSP27 enhances its chaperone activity but also increases aggregation risk, with mutations in an unstructured region linked to neuropathies.

bioRxiv · Jun 14, 2018Biophysics