A short ERK5 isoform modulates nucleocytoplasmic shuttling of active ERK5 and associates with poor survival in breast cancer
M. S. Miranda, J. M. Saunus, S. Akgül, M. Moradi Marjaneh, J. R. Kutasovic, W. Shi, O. Chatterjee, F. Casciello, E. Rozali, H. Y. Handoko, A. P. Wiegmans, T. Liu, J. S. Lee, B. W. Day, S. Edwards, , F. Al-Ejeh
This paper identifies a short ERK5 isoform that promotes extranuclear localization of active ERK5, driving EMT and poor survival in breast cancer.
bioRxiv · Mar 23, 2021Cancer Biology