Author

B. W. Day

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2

Frequent Co-Authors

B. W. Stringer· 3 shared J. M. Saunus· 2 shared S. R. Lakhani· 2 shared A. E. McCart Reed· 1 shared A. P. Wiegmans· 1 shared A.-L. Possmayer· 1 shared B. Linder· 1 shared B. Wainwright· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersCancer Biology

B. W. Stringer

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines

M. Lozinski, N. A. Bowden, M. C. Graves, M. Fay, B. W. Day, B. W. Stringer, P. A. Tooney

This study shows that ATR inhibition with gartisertib enhances cell death and synergizes with TMZ and RT in glioblastoma cell lines, particularly in TMZ-resistant cells.

bioRxiv · Nov 2, 2023Cancer Biology

Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells

S. Rehbein, A.-L. Possmayer, S. Bozkurt, C. Lotsch, J. Gerstmeier, M. Burger, S. Momma, C. Maletzki, C.-F. Classen, T. M. Freiman, D. Dubinski, K. Lamszus, B. W. Day, B. W. Stringer, C. Herold-Mende, , B. Linder

The paper investigates Calcitriol's effect on glioma stem-like cells, finding that some cell lines are sensitive while others are resistant, linked to Vitamin D3 receptor polymorphisms and proteomic changes.

bioRxiv · May 16, 2023Cancer Biology

Targeting OLIG2 increases therapeutic responses in SHH medulloblastoma mouse models and patient-derived medulloblastoma organoids

Y. Li, T. Dismuke, C. Lim, Z. C. Bruce, C. Offenhauser, U. Baumgartner, M. Maybury, R. C. J. DSouza, T. Hassall, B. Wainwright, G. Stein, M. Piper, T. G. Johns, M. Sokolsky-Papkov, T. R. Gershon, B. W. Day

This study shows that targeting OLIG2 with CT-179 reduces recurrence in SHH medulloblastoma models and improves survival when combined with radiotherapy.

bioRxiv · Feb 14, 2022 · PreprintCancer Biology

A short ERK5 isoform modulates nucleocytoplasmic shuttling of active ERK5 and associates with poor survival in breast cancer

M. S. Miranda, J. M. Saunus, S. Akgül, M. Moradi Marjaneh, J. R. Kutasovic, W. Shi, O. Chatterjee, F. Casciello, E. Rozali, H. Y. Handoko, A. P. Wiegmans, T. Liu, J. S. Lee, B. W. Day, S. Edwards, , F. Al-Ejeh

This paper identifies a short ERK5 isoform that promotes extranuclear localization of active ERK5, driving EMT and poor survival in breast cancer.

bioRxiv · Mar 23, 2021Cancer Biology

Immunophenotyping of HER4/YAP axis in breast cancer brain metastasis

P. Kalita-de Croft, M. Lim, X. M. de Luca, B. W. Day, J. M. Saunus, S. R. Lakhani

This study investigates the HER4/YAP axis in breast cancer brain metastasis using patient samples, finding HER4 phosphorylation is specific to BrM but YAP phosphorylation is not a major consequence of HER4 activation.

bioRxiv · Jan 29, 2020 · PreprintPathology

Direct evidence for transport of RNA from the mouse brain to the germline and offspring

E. A. O'Brien, K. S. Ensbey, B. W. Day, P. A. Baldock, G. Barry

This study demonstrates that somatic RNA from the mouse brain can be transported to the germline and passed to offspring.

bioRxiv · Sep 13, 2019Evolutionary Biology

Transcription factors NFIA and NFIB induce cellular differentiation high-grade astrocytoma

K.-S. Chen, J. Bunt, C. R. Bridges, Z. Lynton, J. W. C. Lim, B. W. Stringer, R. Rajagopal, K.-T. Wong, D. Ganesan, H. Ariffin, B. W. Day, L. J. Richards

This study shows that NFIA and NFIB promote differentiation in high-grade astrocytoma by reducing their expression in glioblastomas and inducing differentiation in xenografts.

bioRxiv · Jul 3, 2019Cancer Biology