Author

E. Rynes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. Haugen· 2 shared A. Johnson· 1 shared A. Reynolds· 1 shared C. P. Miller· 1 shared D. Bates· 1 shared D. Dunn· 1 shared D. Hoerl· 1 shared G. Wedemann· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

E. Haugen

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2 papers

Recent·Most cited

Differences in nanoscale organization of DNase I hypersensitive and insensitive chromatin in single human cells

K. Brandstetter, T. Zuelske, T. Ragoczy, D. Hoerl, E. Haugen, E. Rynes, J. A. Stamatoyannopoulos, H. Leonhardt, G. Wedemann, H. Harz

The paper uses microscopy and modeling to study nanoscale chromatin organization in human cells, finding cell-to-cell differences in both active and inactive regions.

bioRxiv · May 27, 2021 · PreprintCell Biology

Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma

K. T. Siebenthall, C. P. Miller, J. D. Vierstra, J. Mathieu, M. Tretiakova, A. Reynolds, R. Sandstrom, E. Rynes, S. J. Neph, E. Haugen, A. Johnson, J. Nelson, D. Bates, M. Diegel, D. Dunn, , S. Akilesh

The paper identifies a HIF-pathway-responsive cryptic promoter driving POU5F1 expression in RCC, linked to poor patient outcomes.

bioRxiv · Jul 27, 2018Cancer Biology