Author

D. Dunn

University of Bristol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Johnson· 1 shared A. L. Harris· 1 shared A. Reynolds· 1 shared A. Wells· 1 shared Alex Hughes-GamesiD· 1 shared B. Verma· 1 shared C. C. Mendes· 1 shared C. P. Miller· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Johnson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Individual Staphylococcus aureus SauUSI restriction endonuclease motors fragment methylated DNA

S.J. Shaw, Alex Hughes-Games, Oscar Enrique Torres Montaguth, S. McDowall, Fiona M. Diffin, D. Dunn, Stephen Cross, Mark D. Szczelkun

This study investigates how the Staphylococcus aureus SauUSI restriction enzyme recognizes and cleaves methylated DNA through ATP-driven translocation and loop formation.

bioRxiv · Oct 16, 2025 · PreprintMicrobiology

APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes

P. J. Singh, B. Verma, A. Wells, C. C. Mendes, D. Dunn, Y.-N. Chen, J. Oh, L. Blincowe, M. Wainwright, R. Fischer, S.-J. Fan, A. L. Harris, D. C. Goberdhan, C. Wilson

The paper shows APP and Aβ-peptides modulate protein aggregation and DCG biogenesis in Drosophila cells, with mutant Aβ-peptides disrupting these processes and causing AD-like pathologies.

bioRxiv · Mar 28, 2024 · PreprintCell Biology

Cryptic Promoter Activation Drives POU5F1 (OCT4) Expression in Renal Cell Carcinoma

K. T. Siebenthall, C. P. Miller, J. D. Vierstra, J. Mathieu, M. Tretiakova, A. Reynolds, R. Sandstrom, E. Rynes, S. J. Neph, E. Haugen, A. Johnson, J. Nelson, D. Bates, M. Diegel, D. Dunn, , S. Akilesh

The paper identifies a HIF-pathway-responsive cryptic promoter driving POU5F1 expression in RCC, linked to poor patient outcomes.

bioRxiv · Jul 27, 2018Cancer Biology