Cancer BiologyThe CRISPR JournalPeer-reviewed
VHL Synthetic Lethality Signatures Uncovered by Genotype-specific CRISPR-Cas9 Screens
N. Sun, S. Petiwala, C. Lu…·N. Chung
The paper uses CRISPR-Cas9 screens in isogenic ccRCC cell lines to identify synthetic lethal partners of VHL, revealing new therapeutic targets for renal cell carcinoma.
DOI 10.1089/crispr.2019.0018