YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis
S. Thomann, S. M. Weiler, S. Marquard, C. R. Ball, M. Toth, T. Wei, C. Sticht, C. de la Torre, E. Ryschich, O. Ermakova, C. Mogler, D. N. Kazdal, N. Gretz, H. Glimm, E. Rempel, , K. Breuhahn
This study shows YAP promotes liver tumor progression by altering the vascular niche, creating heterotypic communication between endothelial cell subtypes via HGF/c-MET signaling.
bioRxiv · Mar 17, 2020Cancer Biology