Cancer BiologybioRxiv
Methylthioadenosine is Not Dramatically Elevated in MTAP-Homozygous Deleted Primary Glioblastomas
Y. Barekatain, V. C. Yan, J. J. Ackroyd…·F. L. Muller
This paper shows that MTA levels are not significantly elevated in MTAP-homozygous deleted primary human glioblastomas, challenging the clinical relevance of targeting PRMT5 and MAT2A in these tumors.
DOI 10.1038/s41467-021-24240-3