Author

E. Simental

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Buchwalter· 1 shared B. Al-Sady· 1 shared B. Panning· 1 shared Barbara Panning· 1 shared C. Allen· 1 shared C. Li· 1 shared E. A. Martin· 1 shared E. Martin· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Buchwalter

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2 papers

Recent·Most cited

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate

H. Marin, E. Simental, C. Allen, E. Martin, B. Panning, B. Al-Sady, A. Buchwalter

The paper shows that the nuclear periphery represses H3K9me2-marked genes and transposons, and its loss disrupts cell fate transitions in mESCs.

bioRxiv · Jul 8, 2024Cell Biology

OGT binds a conserved C-terminal domain of TET1 toregulate TET1 activity and function in development

J. Hrit, C. Li, E. A. Martin, E. Simental, M. Goll, Barbara Panning

This study shows OGT enhances TET1 activity and is necessary for TET1 function in development, with implications for metabolism and epigenetic control.

bioRxiv · Apr 7, 2017Biochemistry