Alligamycin A, an unprecedented antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Z. Yang, Y. Qiao, E. Strobech, J. P. Morth, G. Walther, T. S. Jorgensen, G. Peschel, M. A. Rosenbaum, V. Previtali, M. H. Clausen, M. V. Lukassen, C. H. Gotfredsen, O. Kurzai, T. Weber, L. Ding
This paper identifies alligamycin A, a novel antifungal compound from Streptomyces iranensis, and demonstrates its potent antifungal activity against clinically relevant fungi.
bioRxiv · Apr 17, 2024 · PreprintBiochemistry