Cell BiologybioRxiv
Higher-order assembly is a regulatory switch that promotes outer kinetochore recruitment
G. Sissoko, E. Tarasovetc, E. Grishchuk, I. M. Cheeseman
The paper shows that higher-order assembly of CENP-T promotes outer kinetochore recruitment by increasing local density, thereby restricting kinetochore formation to centromeres.
DOI 10.1038/s41556-023-01313-7