Cancer BiologybioRxivPreprint
SMARCB1 loss creates patient-specific MYC topologies that drive malignant rhabdoid tumor growth
N. Q. Liu, I. Paassen, L. Custers…·J. Drost
This study shows that SMARCB1 loss leads to patient-specific MYC enhancer looping, driving MRT growth through epigenetic reprogramming.