ImmunologybioRxiv
Functional degradation: a mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
A. Sandstrom, P. S. Mitchell, L. Goers…·R. E. Vance
The paper identifies proteasome-mediated degradation of NLRP1B as a mechanism by which two distinct pathogen enzymes activate the inflammasome.
DOI 10.1126/science.aau1330