Quantifying Amide-Aromatic Interactions at Molecular and Atomic Levels: Experimentally-determined Enthalpic and Entropic Contributions to Interactions of Amide sp2O, N, C and sp3C Unified Atoms with Naphthalene sp2C Atoms in Water
E. Zytkiewicz, I. A. Shkel, X. Cheng, A. Rupanya, K. McClure, R. Karim, S. Yang, F. Yang, T. Record
The paper quantifies enthalpic and entropic contributions of amide-aromatic interactions in water, revealing their thermodynamic driving forces and relevance to protein processes.
bioRxiv · Jul 12, 2023 · PreprintBiochemistry