NeurosciencebioRxivPreprint
Lateral Entorhinal Cortex Dysfunction in Alzheimer's Disease Mice
Radha Raghuraman, Andrew Aoun, Mathieu Herman…·S. Abid Hussaini
This study shows that AD pathology in the lateral entorhinal cortex (LEC) causes hyperactive neurons with poor firing fidelity and object coding defects, leading to LEC-specific memory impairments in a transgenic mouse model.
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