NeuroscienceActa NeuropathologicaPeer-reviewed
The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension
Isil Keskin, Elin Forsgren, Manuela Lehmann…·Jonathan D. Gilthorpe
This study shows that low oxygen tension promotes SOD1 misfolding and aggregation in ALS-related cells, linking oxygen levels to disease pathogenesis.
27 citations