Elizabeth Wash

This study shows that micafungin exposure selects for multidrug resistance in C. lusitaniae through mutations in ERG3, leading to sterol reprogramming and cell wall remodeling.

This study analyzes genomic variation in serial Candida albicans isolates from patients, identifying aneuploidy, polyploidy, and loss of heterozygosity as factors driving antifungal drug tolerance.

This study analyzes Candida bloodstream isolates from multiple hospitals, identifying species distribution, antifungal resistance patterns, and within-patient variability in drug susceptibility.

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.