BiochemistrybioRxivPreprint
Characterization of the p38α MAPK allosteric inhibition by a single chain Fv antibody
Emilie Renaud, Marion Larroque, Nicole Bec…·Laurence Guglielmi
This paper identifies a single-chain Fv antibody that allosterically inhibits p38α MAPK by binding to a site distinct from the ATP-binding pocket, reducing inflammation in THP-1 cells.
DOI 10.64898/2026.01.06.697868