Cell BiologybioRxivPreprint
Unc 51-like autophagy-activating kinase (ULK1) mediates clearance of free {alpha}-globin in {beta}-thalassemia
Christophe Lechauve, Julia Keith, Eugene Khandros…·Mitchell J. Weiss
Rapamycin alleviates β-thalassemia by stimulating ULK1-dependent autophagy of toxic free α-globin.