BiochemistryMolecular Systems BiologyPeer-reviewed
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations
Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak…·Ylva Ivarsson
The paper characterizes how disease mutations in intrinsically disordered regions modulate protein interactions mediated by short linear motifs, identifying both loss and gain of interactions.
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