BioinformaticsbioRxivPreprint
Longitudinal structural variant phylogenies define tumor evolution under therapeutic selection pressure in metastatic prostate cancer
YunZhou Liu, Jiaying Lai, Yi Yang…·Rachel Karchin
SVCFit estimates SV cellular fractions from bulk sequencing to reconstruct clonal evolution in mCRPC under therapy, showing treatment-driven clonal reconfiguration.
DOI 10.1101/2025.02.01.636056