Author

Eoin M Gaffney

Princeton University

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Synthetic Biology· 1

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Approach:experimental assay· 1

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Jerelle A. JosephiD· 1 shared José L. Avalos‬iD· 1 shared Ka‐Hei SiuiD· 1 shared Mackenzie T. WallsiD· 1 shared Virginia JiangiD· 1 shared

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Jerelle A. JosephORCID

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Synthetic BiologybioRxivPreprintApr 27, 2026

Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs)

Ka‐Hei Siu, Virginia Jiang, Eoin M Gaffney…·José L. Avalos‬

The paper demonstrates that synthetic membrane-associated condensates (sMACs) can be engineered to enhance metabolic functions by creating localized redox microenvironments through cofactor partitioning.

DOI 10.64898/2026.04.24.720695

experimental assay

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