Molecular BiologybioRxivPreprint
Cutting Through the Artifacts: Dissecting gRNA Impurities with FUSS-seq
Antonino Montalbano, Huan Qiu, Lakshmi Karthik…·Eric Gunnar Anderson
The paper identifies sequencing artifacts in gRNA purity assessment and introduces FUSS-seq to reduce them, improving accuracy for CRISPR-based therapeutics.
DOI 10.1101/2025.09.13.676056