ImmunologybioRxivPreprint
Co-delivered PD-L1 rescues the protective efficacy mediated by an AAV-expressed HIV-1 bNAb
Michael Kuipa, Abubakarr A. Koroma, I. Leguizamo…·Matthew R. Gardner
This study shows that co-delivering PD-L1 with an AAV-expressed HIV-1 bNAb reduces anti-drug antibodies and improves bNAb expression and protection against HIV in rhesus macaques.
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