Single cell transcriptional characterization of human megakaryocyte lineage commitment and maturation
F. A. Choudry, F. Otzen Bagger, I. C. Macaulay, S. Farrow, F. Burden, C. Kempster, H. McKinney, L. R. Olsen, N. Huang, K. Downes, T. Voet, R. Uppal, J. Martin, A. Mathur, W. h. Ouwehand, , M. Frontini
This study uses single-cell RNA sequencing to analyze human bone marrow HSCs and MKs, identifying MK primed HSC clusters and transcriptional changes during MK maturation and their association with myocardial infarction.
bioRxiv · Feb 20, 2020 · PreprintCell Biology