BiophysicsbioRxiv
Statistical Mechanical Prediction of Ligand Perturbation to RNA Secondary Structure and Application to the SAM-I Riboswitch
The paper develops a statistical mechanical model to predict how ligand binding perturbs RNA secondary structure, applied to the SAM-I riboswitch to show subtle conformational shifts rather than an on/off switch.
DOI 10.1002/jcc.26195