Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments
W. Oosterheert, F. Blanc, A. Roy, A. Belyy, O. Hofnagel, G. Hummer, P. Bieling, S. Raunser
This study identifies a molecular backdoor mechanism for inorganic phosphate release from actin filaments, showing how a disease-linked mutation alters Pi release rates and filament structure.
bioRxiv · Mar 25, 2023Biochemistry