Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies
F. Bohr, S. S. R. Bohr, N. K. Mishra, N. S. G. Foutel, H. D. Pinholt, S. Wu, E. M. Nirlsen, M. Zhang, M. Kjaergaard, K. J. Jensen, N. S. Hatzakis
This study uses single molecule fluorescence microscopy to observe insulin self-assembly and disassembly, revealing new pathways and how additives influence oligomer formation.
bioRxiv · Apr 6, 2022Biophysics