Author

F. Facchinetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. De Toma· 1 shared C. Camisaschi· 1 shared C. Chiodoni· 1 shared C. D'Alterio· 1 shared C. Tripodo· 1 shared D. Zhang· 1 shared F. Giovinazzo· 1 shared G. Bertolini· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. De Toma

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Author profile →

2 papers

Recent·Most cited

Transferrin Receptor Targeting Chimeras (TransTACs) for Membrane Protein Degradation

D. Zhang, J. Duque-Jimenez, G. Brixi, F. Facchinetti, K. Rhee, W. W. Feng, P. A. Jänne, X. Zhou

This paper introduces TransTACs, a method for degrading membrane proteins by redirecting them to lysosomal degradation using the transferrin receptor, showing high efficiency across various protein types.

bioRxiv · Aug 10, 2023Bioengineering

SDF-1/CXCR4 inhibition prevents paradoxical generation of cisplatin-induced pro-metastatic niches

G. Bertolini, V. Cancila, M. Milione, G. Lo Russo, O. Fortunato, N. Zaffaroni, M. Tortoreto, G. Centonze, C. Chiodoni, F. Facchinetti, F. Giovinazzo, M. Moro, C. Camisaschi, A. De Toma, C. D'Alterio, , L. Roz

This study shows that cisplatin promotes metastasis by creating pro-metastatic niches, which can be blocked by CXCR4 inhibition.

bioRxiv · Oct 26, 2020Cancer Biology