Tension causes structural unfolding of intracellular intermediate filaments
F. Fleissner, S. Kumar, N. Klein, D. Wirth, R. Dhiman, D. Schneider, M. Bonn, S. H. Parekh
The paper uses Raman imaging to show that intracellular vimentin unfolds under cellular tension, indicating IFs act as force sensors.
bioRxiv · Apr 22, 2020Biophysics