Vitamin K-dependent carboxylation regulates calcium flux and adaptation to metabolic stress in β-cells
J. Lacombe, K. Guo, J. Bonneau, D. Faubert, F. Gioanni, A. Vivoli, S. M. Muir, S. Hezzaz, V. Poitout, M. Ferron
This study shows that vitamin K-dependent gamma-carboxylation in beta-cells regulates calcium flux and adaptation to metabolic stress by modulating ERGP function.
bioRxiv · May 13, 2022 · PreprintCell Biology