Author

F. Hassler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. E. Sanin· 2 shared E. J. Pearce· 2 shared E. L. Pearce· 2 shared A. Castoldi· 1 shared A. Kabat· 1 shared A. M. Cameron· 1 shared C. S. Field· 1 shared C. Wang· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

D. E. Sanin

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Author profile →

2 papers

Recent·Most cited

Triacylglycerol synthesis enhances macrophage inflammatory function

A. Castoldi, L. B. Monteiro, N. van Teijlingen Bakker, D. E. Sanin, N. Rana, M. Corrado, A. M. Cameron, F. Hassler, M. Matsushita, G. Caputa, R. I. I. Klein Geltink, J. Buscher, J. Edwards-Hicks, E. L. Pearce, E. J. Pearce

This study shows that triacylglycerol synthesis in macrophages is essential for inflammatory function, as inhibiting it reduces proinflammatory cytokines and phagocytic capacity.

bioRxiv · Feb 3, 2020Immunology

Polyamine Metabolism Regulates the T Cell Epigenome Through Hypusination

D. J. Puleston, F. Baixauli, D. E. Sanin, M. Villa, A. Kabat, M. M. Kaminski, H. Weiss, K. Grzes, L. J. Flachsmann, C. S. Field, M. Stanckzak, L. Schimmelpfennig, F. Hassler, C. Wang, N. Yosef, , E. L. Pearce

This study shows that polyamine metabolism, specifically through hypusination, is essential for maintaining T cell subset identity by regulating the epigenome and transcriptional programs.

bioRxiv · Jan 24, 2020 · PreprintImmunology