Author

F. J. Roca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

L. Ramakrishnan· 2 shared A. Pagan· 1 shared E. M. Busch-Nentwich· 1 shared G. Rinaldi· 1 shared G. Schramm· 1 shared J. Fan· 1 shared J. M. F. G. Aerts· 1 shared K. K. Takaki· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

L. Ramakrishnan

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Author profile →

2 papers

Recent·Most cited

Gaucher Disease Protects Against Tuberculosis

J. Fan, V. L. Halre, L. T. Lelieveld, L. J. Whitworth, E. M. Busch-Nentwich, M. Troll, P. H. Edelstein, T. M. Cox, F. J. Roca, J. M. F. G. Aerts, L. Ramakrishnan

This paper shows that the GBA1 N370S mutation, common in Ashkenazi Jews, protects against tuberculosis by enhancing macrophage microbicidal activity through glucosylsphingosine.

bioRxiv · Oct 16, 2022Microbiology

Tumor Necrosis Factor and Schistosoma mansoni egg antigen Omega-1 shape distinct aspects of the early egg-induced granulomatous response

L. Ramakrishnan, K. K. Takaki, F. J. Roca, G. Schramm, R. H. P. Wilbers, W. Ittiprasert, P. J. Brindley, G. Rinaldi, M. Berriman, A. Pagan

This study investigates how TNF and omega-1 from Schistosoma mansoni eggs influence granuloma formation in zebrafish, showing distinct roles in macrophage recruitment and granuloma enlargement.

bioRxiv · Sep 29, 2020Microbiology