F. Jean-Pierre

DPR-MEDIATED H2O2 RESISTANCE CONTRIBUTES TO STREPTOCOCCI SURVIVAL IN A CYSTIC FIBROSIS AIRWAY MODEL SYSTEM

The paper identifies Dpr-mediated H2O2 resistance as critical for Streptococcus sanguinis survival in a polymicrobial CF airway model.

Growing a cystic fibrosis-relevant polymicrobial biofilm to probe community phenotypes.

This paper develops a four-species polymicrobial biofilm model to study interspecies interactions in cystic fibrosis lung infections and observe clinically relevant phenotypes.

Transcriptional Profiling and Genetic Analysis of a Cystic Fibrosis Airway-Relevant Model Shows Asymmetric Responses to Growth in a Polymicrobial Community

The paper compares transcriptional responses of a polymicrobial cystic fibrosis airway community to monocultures under different growth conditions and identifies community-specific gene expression patterns.

Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system

This study develops a polymicrobial biofilm model of the CF lung to investigate community-specific antimicrobial resistance and identifies LasR loss-of-function as a driver of tobramycin tolerance through increased phenazine production.

An experimentally evolved variant of RsmA confirms its central role in the control of Pseudomonas aeruginosa social motility

This study uses experimental evolution to identify mutations in gacA and rsmA that rescue a swarming defect in a Pseudomonas aeruginosa mutant, confirming RsmA's central role in social motility.

Pseudomonas aeruginosa enhances the efficacy of norfloxacin against Staphylococcus aureus biofilms

This study shows that Pseudomonas aeruginosa exoproducts enhance norfloxacin efficacy against Staphylococcus aureus biofilms by increasing drug uptake and reducing efflux.