Author

F. L. Smith

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

H. P. Savage· 1 shared K. Kläsener· 1 shared M. Reth· 1 shared N. Baumgarth· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

H. P. Savage

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1 paper

Recent·Most cited

TLR-induced reorganization of the IgM-BCR complex regulates B-1 cell responses to infections

H. P. Savage, K. Kläsener, F. L. Smith, M. Reth, N. Baumgarth

This study shows TLR activation in CD5+ B-1 cells reorganizes the IgM-BCR complex, leading to CD5 loss and increased BCR signaling, which is necessary for plasmablast differentiation during infections.

bioRxiv · Apr 2, 2019 · PreprintImmunology