A microfluidic strategy to capture antigen-specific high affinity B cells
A. M. Alhassan, V. S. Shirure, J. Luo, B. B. Nguyen, Z. A. Rollins, B. S. Shergill, X. Zhu, N. Baumgarth, S. C. George
This paper introduces a microfluidic method to assess B cell affinity to antigens under force, showing it can enrich high-affinity B cells and correlate with solution-based antibody affinity.
bioRxiv · Jul 12, 2023Bioengineering