Cancer BiologybioRxivPreprint
Chimeric protein EWS-FLI1 drives cell proliferation in Ewing Sarcoma via overexpression of KCNN1.
M. Dupuy, M. Gueguinou, A. Postec…·F. Verrecchia
This study identifies KCNN1 as a target of EWS-FLI1 and EWS-ERG fusion proteins in Ewing Sarcoma, showing its role in cell proliferation and potential as a therapeutic target.
DOI 10.1101/2023.04.24.538050