Author

F. Locatelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. A. Sharma· 1 shared A. Burford· 1 shared A. Carai· 1 shared A. Gagliardi· 1 shared A. Mackay· 1 shared A. Marra· 1 shared A. Martin· 1 shared A. Mastronuzzi· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. A. Sharma

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemia.

G. Corleone, C. Sorino, M. Caforio, S. Di Giovenale, F. De Nicola, V. Bertaina, A. Pitisci, C. Cortile, F. Locatelli, V. Folgiero, M. Fanciulli

This study shows enhancer plasticity drives oncogenic transformation and relapse in B-Cell Acute Lymphoblastic Leukemia by dynamically changing during disease progression.

bioRxiv · May 18, 2022Cancer Biology

Prolonged XPO1 inhibition is essential for optimal anti-leukemic activity in NPM1-mutated AML

G. Pianigiani, A. Gagliardi, F. Mezzasoma, F. Rocchio, V. Tini, B. Bigerna, P. Sportoletti, S. Caruso, A. Marra, G. Spinozzi, S. Shacham, Y. Landesman, C. Quintarelli, F. Locatelli, M. P. Martelli, , L. Brunetti

This study shows that prolonged XPO1 inhibition is more effective than intermittent dosing in NPM1-mutated AML by achieving stable HOX downregulation and anti-leukemic activity.

bioRxiv · Dec 11, 2021 · PreprintCancer Biology

Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

D. Carvalho, S. Temelso, A. Mackay, H. Pemberton, R. Rogers, K. Kessler, E. Izquierdo, L. Bjerke, J. Fazal-Salom, M. Clarke, Y. Grabovska, A. Burford, N. Gene-Olaciregui, J. Boult, V. Molinari, , Hubank

bioRxiv · Dec 29, 2020 · PreprintCancer Biology

Looking for pathways related to COVID-19 phenotypes: Confirmation of pathogenic mechanisms by SARS-CoV-2 - Host interactome.

F. Messina, E. Giombini, C. Montaldo, A. A. Sharma, M. Piacentini, A. Zoccoli, R. P. Sekaly, F. Locatelli, A. Zumla, M. Maeurer, M. R. Capobianchi, F. N. Lauria, G. Ippolito

The paper identifies host-virus interactions and specific SARS-CoV-2 proteins involved in severe COVID-19 phenotypes using network analysis.

bioRxiv · Nov 3, 2020Microbiology