G. Corleone

This study shows enhancer plasticity drives oncogenic transformation and relapse in B-Cell Acute Lymphoblastic Leukemia by dynamically changing during disease progression.

This study identifies Che-1/AATF as a paraspeckle component that regulates R-loop formation and interferon activation in multiple myeloma, linking R-loops to disease progression and poor prognosis.

This study uses single-cell transcriptomics to identify pre-adapted cells that undergo reprogramming to develop resistance to endocrine therapy in breast cancer.

This study maps enhancers in luminal breast cancer to reveal phenotypic heterogeneity and its evolutionary dynamics during treatment.