Limited oxygen availability in standard cell culture alters metabolism and function in terminally-differentiated cells
J. Tan, S. Virtue, D. M. Norris, O. J. Conway, M. Yang, C. Gribben, F. Lutgu, J. R. Krycer, R. J. Mills, I. Kamzolas, C. Pereira, M. Dale, A. S. Shun-Shion, H. J. Baird, J. A. Horscroft, , D. J. Fazakerley
This study shows that increasing oxygen levels in cell culture improves metabolic function and responsiveness in terminally differentiated cells like adipocytes and hepatocytes.
bioRxiv · Nov 29, 2022 · PreprintCell Biology