C. Pereira

The paper develops a high-throughput 3D cardiac tissue assay using human iPSC-derived cardiomyocytes and fibroblasts to study mechanical and drug responses.

This study shows that increasing oxygen levels in cell culture improves metabolic function and responsiveness in terminally differentiated cells like adipocytes and hepatocytes.

This study identifies the exocyst complex as essential for constitutive secretion in mammalian cells by showing its role in carrier fusion and cargo delivery.

This study examines proteome and sugar content changes in Pinus radiata embryogenic tissue after heat treatment to understand thermopriming mechanisms.

This paper identifies PnpA, a secreted NlpC/P60 endopeptidase from Photobacterium damselae subsp. piscicida, which cleaves the peptidoglycan of competing bacteria, suggesting a role in competitive advantage and nutrient acquisition.

This study shows that reprogramming human cells to pluripotency reduces centromeric CENP-A levels, linking centromere dysfunction to stem cell aneuploidy.

This study shows that the RZZ complex self-assembles into filaments to drive kinetochore expansion when microtubules are not attached, facilitating SAC signaling and chromosome segregation.