Author

F. Lyko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:non-human primate· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

G. Raddatz· 3 shared J. Gutekunst· 2 shared M. Rodriguez-Paredes· 2 shared A. K. Miller· 1 shared A. S. Lonsdorf· 1 shared C. I. Wagner· 1 shared C. Legrand· 1 shared F. Boehl· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

G. Raddatz

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Author profile →

5 papers

Recent·Most cited

Time-resolved, integrated analysis of clonally evolving genomes

C. Legrand, R. Andriantsoa, P. Lichter, F. Lyko

The paper develops a framework to infer time-resolved evolutionary parameters from clonal genome data, applying it to marbled crayfish and glioblastoma samples.

bioRxiv · Oct 8, 2021Evolutionary Biology

Physiological properties and tailored feeds to support aquaculture of marbled crayfish in closed systems

S. Toenges, K. Masagounder, J. Gutekunst, J. Lohbeck, A. K. Miller, F. Boehl, F. Lyko

This study evaluates the physiological traits and tailored feeds for marbled crayfish in closed aquaculture systems, finding comparable size to farmed crayfish and a high chitin content with efficient feed conversion.

bioRxiv · Feb 25, 2020Physiology

Single-cell transcriptomes of the aging human skin reveal loss of fibroblast priming

L. Sole-Boldo, G. Raddatz, S. Schuetz, J.-P. Mallm, K. Rippe, A. S. Lonsdorf, M. Rodriguez-Paredes, F. Lyko

The paper uses single-cell RNA sequencing to analyze fibroblast subpopulations in young and old human skin, finding that aging reduces fibroblast priming and alters their interactions with other skin cells.

bioRxiv · May 9, 2019Cell Biology

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

F. Koehler, F. Bormann, G. Raddatz, J. Gutekunst, T. Musch, F. Lyko, M. Rodriguez-Paredes

This study identifies epigenetic deregulation of lamina-associated domains in HGPS patient fibroblasts, linking it to gene expression changes and chromatin alterations.

bioRxiv · Jan 22, 2019Cell Biology

Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

N. K. E. Schulz, C. I. Wagner, J. Ebeling, G. Raddatz, M. F. Diddens-de Buhr, F. Lyko, J. Kurtz

The paper shows Dnmt1 is essential for red flour beetle development despite no CpG methylation, suggesting a non-methyltransferase function.

bioRxiv · Sep 27, 2018Evolutionary Biology