Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
P. Boskovic, N. W. Wilke, P. Lichter, L. Francois, B. Radlwimmer
This study shows BCAT1 promotes glioblastoma growth by blocking differentiation and sustaining immunosuppression, with knockout leading to tumor growth suppression and immune infiltration.
bioRxiv · Apr 28, 2023 · PreprintCancer Biology
L. L. Cid, J. K. Leong, I. F. Botana, Y. Paul, M. Wierz, A. Floerchinger, S. Gonder, G. Pagano, M. Chazotte, K. Bestak, C. Schifflers, M. Iskar, T. Roider, F. Czernilofsky, P.-M. Bruch, , M. Seiffert
The paper defines CLL T cell subtypes and identifies Galectin-9 as a novel immunotherapy target through single-cell and multi-omics analyses.
bioRxiv · Dec 15, 2022 · PreprintCancer Biology
C. Legrand, R. Andriantsoa, P. Lichter, F. Lyko
The paper develops a framework to infer time-resolved evolutionary parameters from clonal genome data, applying it to marbled crayfish and glioblastoma samples.
bioRxiv · Oct 8, 2021Evolutionary Biology
U. Khalid, M. Simovic, M. Iskar, J. K. L. Wong, R. Kumar, M. Jugold, M. Sill, M. Bolkestein, T. Kolb, M. Hergt, F. Devens, J. Ecker, M. Kool, T. Milde, F. Westermann, , A. Ernst
The paper identifies a synergistic effect between HDAC and PARP inhibitors in childhood tumors with chromothripsis, validated through drug screening and in vivo models.
bioRxiv · Apr 22, 2021Cancer Biology
P. M. Roessner, L. LLaó Cid, E. Lupar, T. Roider, M. Bordas, C. Schifflers, A.-C. Gaupel, F. Kilpert, M. Krötschel, S. J. Arnold, L. Sellner, S. Stilgenbauer, S. Dietrich, P. Lichter, A. Izcue, M. Seiffert
bioRxiv · Mar 9, 2020Cancer Biology
M. Zapatka, I. Borozan, D. S. Brewer, M. Iskar, A. Grundhoff, M. Alawi, N. Desai, H. Sueltmann, H. Moch, PCAWG Pathogens Working Group, ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network, C. S. Cooper, R. Eils, V. Ferretti, P. Lichter
The paper systematically investigates viral associations in human cancers using whole-genome and transcriptome data from 2,656 donors, revealing prevalence of known tumor-associated viruses and their genomic impacts.
bioRxiv · Sep 9, 2019Cancer Biology
M. Ratnaparkhe, J. Wong, P.-C. Wei, M. Hlevnjak, T. Kolb, D. Haag, Y. Paul, F. Devens, P. Northcott, D. T. Jones, M. Kool, A. Jauch, A. Pastorczak, W. Mlynarski, A. Korshunov, , A. Ernst
The paper identifies chromothripsis and chromoanasynthesis in tumors with DNA repair deficiencies and links them to MYC/MYCN amplification and therapeutic opportunities.
bioRxiv · May 4, 2018Cancer Biology