Author

F. Maina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. Ahmad· 2 shared F. Lamballe· 2 shared G. B. Mills· 2 shared O. Castellanet· 2 shared S. Lev· 2 shared Y. Vinik· 2 shared A. Harou· 1 shared A. Mueller· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersCancer Biology

F. Ahmad

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ecophysiological genomics identifies a pleiotropic locus mediating drought tolerance in sorghum

F. Maina, A. Harou, F. Hamidou, G. P. Morris

This study identifies a pleiotropic locus associated with drought tolerance in sorghum using GWAS, revealing genetic variants linked to yield components and water use under drought.

bioRxiv · Dec 3, 2021 · PreprintPlant Biology

Disruption of Epithelial Integrity Drives Mesendoderm Differentiation in Human Induced Pluripotent Stem Cells by Enabling BMP and ACTIVIN Sensing

D. Rattier, T. Legier, T. Vannier, F. Maina, R. DONO

This study shows that disrupting epithelial integrity in hiPSCs enables BMP and ACTIVIN signaling, driving mesendoderm differentiation.

bioRxiv · Oct 22, 2021 · PreprintCell Biology

BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

O. Castellanet, F. Ahmad, Y. Vinik, G. B. Mills, B. H. Habermann, J.-P. H. Borg, S. Lev, F. Lamballe, F. Maina

This study shows that blocking BCL-XL makes TNBC cells vulnerable to CDK1/2/4 inhibitors, but not other cell cycle regulators, through synergistic effects on survival and apoptosis pathways.

bioRxiv · Mar 16, 2021Cancer Biology

Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

F. Lamballe, F. Ahmad, Y. Vinik, O. Castellanet, F. Daian, A. Mueller, U. Koehler, A.-L. Bailly, E. Josselin, R. Castellano, C. Cayrou, E. Charafe-Jauffret, G. B. Mills, V. Geli, J.-P. Borg, , F. Maina

This study develops a mouse model of TNBC that recapitulates human tumor heterogeneity and identifies a synergistic combination of WEE1 and BCL-XL inhibition as a potential treatment.

bioRxiv · Jun 22, 2020Cancer Biology