Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
N. Chotiwan, E. Rosendal, S. M. A. Willekens, E. Schexnaydre, E. Nilsson, R. Lindqvist, M. Hahn, I. S. Mihai, F. Morini, J. Zhang, G. Ebel, L.-A. Carlson, J. Henriksson, U. Ahlgren, D. Marcellino, A. K. Overby
The paper uses multimodal imaging and single nuclei RNA-sequencing to study how type I interferon affects viral tropism in the brain during flavivirus infection in mice.
bioRxiv · Nov 16, 2021Microbiology