Author

N. Chotiwan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:Arabidopsis· 2 Assay:imaging· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. Lian· 3 shared R. Perera· 3 shared G. Ramirez· 2 shared R. C. Gullberg· 2 shared A. Hopf-Jannasch· 1 shared A. K. Overby· 1 shared A. Nag· 1 shared B. Graham· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

E. Lian

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Differential intra-host infection kinetics in Aedes aegypti underlie superior transmissibility of African relative to Asian Zika virus

R. Phengchat, P. Pakparnich, C. Pethrak, J. Pengon, C. Sartsanga, N. Chotiwan, K. Uppakara, K. Suksirisawat, L. Lambrechts, N. Jupatanakul

This study compares intra-host infection kinetics of African and Asian Zika virus in Aedes aegypti, finding the African lineage replicates faster and spreads more efficiently.

bioRxiv · May 24, 2023 · PreprintMicrobiology

Shifting a Cellular Metabolic Landscape Identifies a Refractory Environment for Flavivirus Replication

R. C. Gullberg, N. Chotiwan, M. N. Islam, L. St Clair, E. Lian, T. J. Edwards, S. Khadka, C. Teng, B. Graham, K. Krieger, A. Hopf-Jannasch, D. J. LaCount, J. T. Belisle, R. J. Kuhn, R. Perera

The paper identifies a refractory metabolic environment induced by fatty acid biosynthesis inhibition that limits flavivirus replication and shows that combining this with nucleotide synthesis pathway inhibition significantly reduces viral infectivity.

bioRxiv · Feb 21, 2022 · PreprintMicrobiology

Expression of fatty acid synthase genes and their role in development and arboviral infection of Aedes aegypti

N. Chotiwan, C. A. Brito-Sierra, G. Ramirez, E. Lian, C. A. Hill, R. Perera

This study identifies and characterizes FAS genes in Aedes aegypti, showing AaFAS1's role in dengue virus infection and transmission.

bioRxiv · Feb 14, 2022Microbiology

Acyl-CoA Thioesterases; a rheostat that controls activated fatty acids modulates dengue virus serotype 2 replication

L. A. St Clair, S. A. Mills, E. Lian, P. S. Soma, A. Nag, C. Montgomery, G. Ramirez, N. Chotiwan, R. C. Gullberg, R. Perera

This study investigates the role of acyl-CoA thioesterases (ACOTs) in modulating dengue virus serotype 2 replication, showing that their loss of function affects viral replication and infectious particle release.

bioRxiv · Dec 12, 2021Microbiology

Type I interferon shapes brain distribution and tropism of tick-borne flavivirus

N. Chotiwan, E. Rosendal, S. M. A. Willekens, E. Schexnaydre, E. Nilsson, R. Lindqvist, M. Hahn, I. S. Mihai, F. Morini, J. Zhang, G. Ebel, L.-A. Carlson, J. Henriksson, U. Ahlgren, D. Marcellino, A. K. Overby

The paper uses multimodal imaging and single nuclei RNA-sequencing to study how type I interferon affects viral tropism in the brain during flavivirus infection in mice.

bioRxiv · Nov 16, 2021Microbiology