Meat enriched-diet and inflammation promote PI3Kα-dependent pancreatic cell plasticity that limit tissue regeneration.
C. Cayron, D. Bozoglou, A. V. Villard, G. Reyes-Castellanos, N. Therville, R. Baer, S. Arcucci, N. Naud, M. Tosolini, F. Pont, D. Ferreira Da Mota, F. Gueraud, C. Basset, A. Carrier, F. Pierre, , J. Guillermet-Guibert
This study shows that meat-enriched diets and inflammation promote pancreatic cell plasticity via PI3Kα, which limits tissue regeneration and increases cancer risk.
bioRxiv · Aug 22, 2023 · PreprintPathology