Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin
Z. T. Berndsen, M. Akhtar, M. Thapa, T. J. Vickers, A. Schmitz, J. Torres, P. Kumar, N. Khatoon, A. Sheikh, M. Hamrick, J. Diedrich, S. Martinez-Bartolome, P. Garrett, J. Yates, J. Turner, , J. M. Fleckenstein
This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.
bioRxiv · May 8, 2024 · PreprintMicrobiology