Tension promotes kinetochore-microtubule release in response to Aurora B activity
G.-Y. Chen, F. Renda, H. Zhang, A. Gokden, D. Z. Wu, D. M. Chenoweth, A. Khodjakov, M. Lampson
The paper shows that Aurora B kinase activity leads to kinetochore-microtubule release under high tension and depolymerization under low tension, suggesting tension-dependent error correction mechanisms.
bioRxiv · Jun 1, 2020Cell Biology