Author

F. Sampaziotis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. Vallier· 2 shared A. J. Butler· 1 shared A. M. Moon· 1 shared A. Munteanu· 1 shared A. P. Davenport· 1 shared A. Shahsavari· 1 shared A. W. Lohse· 1 shared B. T. Wesley· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

L. Vallier

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Author profile →

2 papers

Recent·Most cited

Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

C. M. Morell, S. G. Tilson, R. A. Tomaz, A. Shahsavari, A. Munteanu, G. Canu, B. T. Wesley, M. Perrin, I. Geti, S. Mukhopadhyay, F. Mazzacuva, P. Gissen, J. Garcia-Bernardo, M. Bachman, C. A. Rimland, , L. Vallier

This paper develops a 3D multicellular model of NAFLD using hiPSC-derived liver cells to study disease mechanisms and interactions.

bioRxiv · Feb 7, 2024 · PreprintCell Biology

FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome

T. Brevini, M. Maes, G. J. Webb, W. T. H. Gelson, S. Forrest, P. Mlcochova, S. Dillon, S. Varankar, M. Darvish-Damavandi, V. L. Mulcahy, R. E. Kuc, T. L. Williams, V. Galanakis, M. Vila-Gonzalez, O. C. Tysoe, , F. Sampaziotis

This study shows FXR inhibition lowers ACE2 expression, reduces SARS-CoV-2 infection, and correlates with better clinical outcomes in COVID-19.

bioRxiv · Jun 6, 2021 · PreprintMicrobiology